Improving Visual Field Examination of the Macula Using Structural Information

Purpose: To investigate a novel approach for structure-function modeling in glaucoma to improve visual field testing in the macula. Methods: We acquired data from the macular region in 20 healthy eyes and 31 with central glaucomatous damage. Optical coherence tomography (OCT) scans were used to estimate the local macular ganglion cell density. Perimetry was performed with a fundus-tracking device using a 10-2 grid. OCT scans were matched to the retinal image from the fundus perimeter to accurately map the tested locations onto the structural damage. Binary responses from the subjects to all presented stimuli were used to calculate the structure-function model used to generate prior distributions for a ZEST (Zippy Estimation by Sequential Testing) Bayesian strategy. We used simulations based on structural and functional data acquired from an independent dataset of 20 glaucoma patients to compare the performance of this new strategy, structural macular ZEST (MacS-ZEST), with a standard ZEST. Results: Compared to the standard ZEST, MacS-ZEST reduced the number of presentations by 13% in reliable simulated subjects and 14% with higher rates (≥20%) of false positive or false negative errors. Reduction in mean absolute error was not present for reliable subjects but was gradually more important with unreliable responses (≥10% at 30% error rate). Conclusions: Binary responses can be modeled to incorporate detailed structural information from macular OCT into visual field testing, improving overall speed and accuracy in poor responders. Translational Relevance: Structural information can improve speed and reliability for macular testing in glaucoma practice

Back and forth from cool core to non-cool core: clues from radio-halos

X-ray astronomers often divide galaxy clusters into two classes: "cool core" (CC) and "non-cool core" (NCC) objects. The origin of this dichotomy has been the subject of debate in recent years, between "evolutionary" models (where clusters can evolve from CC to NCC, mainly through mergers) and "primordial" models (where the state of the cluster is fixed "ab initio" by early mergers or pre-heating). We found that in a well-defined sample (clusters in the GMRT Radio halo survey with available Chandra or XMM-Newton data), none of the objects hosting a giant radio halo can be classified as a cool core. This result suggests that the main mechanisms which can start a large scale synchrotron emission (most likely mergers) are the same that can destroy CC and therefore strongly supports "evolutionary" models of the CC-NCC dichotomy. Moreover combining the number of objects in the CC and NCC state with the number of objects with and without a radio-halo, we estimated that the time scale over which a NCC cluster relaxes to the CC state, should be larger than the typical life-time of radio-halos and likely shorter than about 3 Gyr. This suggests that NCC transform into CC more rapidly than predicted from the cooling time, which is about 10 Gyr in NCC systems, allowing the possibility of a cyclical evolution between the CC and NCC states.Comment: Accepted for publication in A&

Radio emission at the centre of the galaxy cluster Abell 3560: evidence for core sloshing?

Previous radio observations of the galaxy cluster A3560 in the Shapley Concentration showed complex radio emission associated with the brightest cluster member.To understand its origin we observed it with the GMRT, the VLA and ATCA at 240 and 610 MHz, 1.28,1.4, 2.3,4.8 and 8.4 GHz, and performed a detailed morphological and spectral study of the radio emission associated with the BCG. We also observed the cluster with XMM-Newton and Chandra to derive the properties of the ICM. The radio emission of the N-E nucleus of the dumb-bell BCG shows an active radio galaxy, plus aged diffuse emission, which is not refurbished at present. Our Chandra data show that the radio active nucleus of the BCG has extended X-ray emission, which we classify as a low-luminosity corona. A residual image of the XMM-Newton brightness shows the presence of a spiral-like feature, which we interpret as the signature of gas sloshing. The presence of a subgroup is clear in the surface brightness residual map, and in the XMM-Newton temperature analysis. The optical 2D analysis shows substructure in A3560. A galaxy clump was found at the location of the X-ray subgroup, and another group is present south of the cluster core, close to the spiral-like feature. The aged part of the radio emission closely follows the spiral pattern of the X-ray residual brightness distribution, while the two active radio lobes are bent in a completely different direction. We conclude that the complex radio emission associated with the cluster BCG is the result of a minor merger event in A3560. The aged diffuse emission is strongly affected by the sloshing motion in the ICM. On the other hand, the bent jets and lobes of the current radio AGN activity may reflect a complex gas velocity field in the innermost cluster regions and/or sloshing-induced oscillations in the motion of the cD galaxy.Comment: 15 pages, 8 figures, 5 tables, A&A in pres

Mass profiles and concentration-dark matter relation in X-ray luminous galaxy clusters

(Abriged) Assuming that the hydrostatic equilibrium holds between the intracluster medium and the gravitational potential, we constrain the NFW profiles in a sample of 44 X-ray luminous galaxy clusters observed with XMM-Newton in the redshift range 0.1-0.3. We evaluate several systematic uncertainties that affect our reconstruction of the X-ray masses. We measure the concentration c200, the dark mass M200 and the gas mass fraction within R500 in all the objects of our sample, providing the largest dataset of mass parameters for galaxy clusters in this redshift range. We confirm that a tight correlation between c200 and M200 is present and in good agreement with the predictions from numerical simulations and previous observations. When we consider a subsample of relaxed clusters that host a Low-Entropy-Core (LEC), we measure a flatter c-M relation with a total scatter that is lower by 40 per cent. From the distribution of the estimates of c200 and M200, with associated statistical (15-25%) and systematic (5-15%) errors, we use the predicted values from semi-analytic prescriptions calibrated through N-body numerical runs and measure sigma_8*Omega_m^(0.60+-0.03)= 0.45+-0.01 (at 2 sigma level, statistical only) for the subsample of the clusters where the mass reconstruction has been obtained more robustly, and sigma_8*Omega_m^(0.56+-0.04) = 0.39+-0.02 for the subsample of the 11 more relaxed LEC objects. With the further constraint from the fgas distribution in our sample, we break the degeneracy in the sigma_8-Omega_m plane and obtain the best-fit values sigma_8~1.0+-0.2 (0.75+-0.18 when the subsample of the more relaxed objects is considered) and Omega_m = 0.26+-0.01.Comment: 21 pages. A&A in press. Minor revisions to match accepted version. Corrected 2nd and 3rd column in Table 3, and equation (A.4

Gas clumping in galaxy clusters

The reconstruction of galaxy cluster's gas density profiles is usually performed by assuming spherical symmetry and averaging the observed X-ray emission in circular annuli. In the case of a very inhomogeneous and asymmetric gas distribution, this method has been shown to return biased results in numerical simulations because of the $n^2$ dependence of the X-ray emissivity. We propose a method to recover the true density profiles in the presence of inhomogeneities, based on the derivation of the azimuthal median of the surface brightness in concentric annuli. We demonstrate the performance of this method with numerical simulations, and apply it to a sample of 31 galaxy clusters in the redshift range 0.04-0.2 observed with ROSAT/PSPC. The clumping factors recovered by comparing the mean and the median are mild and show a slight trend of increasing bias with radius. For $R<R_{500}$, we measure a clumping factor $\sqrt{C}<1.1$, which indicates that the thermodynamic properties and hydrostatic masses measured in this radial range are only mildly affected by this effect. Comparing our results with three sets of hydrodynamical numerical simulations, we found that non-radiative simulations significantly overestimate the level of inhomogeneities in the ICM, while the runs including cooling, star formation, and AGN feedback reproduce the observed trends closely. Our results indicate that most of the accretion of X-ray emitting gas is taking place in the diffuse, large-scale accretion patterns rather than in compact structures.Comment: 12 pages, 11 figures, accepted for publication in MNRAS. Largely-improved version compared to v1, method and comparison with simulations update

The cool core state of Planck SZ-selected clusters versus X-ray selected samples: evidence for cool core bias

We characterized the population of galaxy clusters detected with the SZ effect with Planck, by measuring the cool core state of the objects in a well-defined subsample of the Planck catalogue. We used as indicator the concentration parameter Santos et al. (2008). The fraction of cool core clusters is $29 \pm 4 \%$ and does not show significant indications of evolution in the redshift range covered by our sample. We compare the distribution of the concentration parameter in the Planck sample with the one of the X-ray selected sample MACS (Mann & Ebeling, 2011): the distributions are significantly different and the cool core fraction in MACS is much higher ($59 \pm 5 \%$). Since X-ray selected samples are known to be biased towards cool cores due to the presence of their prominent surface brightness peak, we simulated the impact of the "cool core bias" following Eckert et al. (2011). We found that it plays a large role in the difference between the fractions of cool cores in the two samples. We examined other selection effects that could in principle bias SZ-surveys against cool cores but we found that their impact is not sufficient to explain the difference between Planck and MACS. The population of X-ray under-luminous objects, which are found in SZ-surveys but missing in X-ray samples (Planck Collaboration 2016), could possibly contribute to the difference, as we found most of them to be non cool cores, but this hypothesis deserves further investigation.Comment: Accepted for publication in MNRA

Torsion free groups with indecomposable holonomy group I

We study the torsion free generalized crystallographic groups with the indecomposable holonomy group which is isomorphic to either a cyclic group of order ${p^s}$ or a direct product of two cyclic groups of order ${p}$.Comment: 22 pages, AMS-Te

A textbook example of ram-pressure stripping in the Hydra A/A780 cluster

In the current epoch, one of the main mechanisms driving the growth of galaxy clusters is the continuous accretion of group-scale halos. In this process, the ram pressure applied by the hot intracluster medium on the gas content of the infalling group is responsible for stripping the gas from its dark-matter halo, which gradually leads to the virialization of the infalling gas in the potential well of the main cluster. Using deep wide-field observations of the poor cluster Hydra A/A780 with XMM-Newton and Suzaku, we report the discovery of an infalling galaxy group 1.1 Mpc south of the cluster core. The presence of a substructure is confirmed by a dynamical study of the galaxies in this region. A wake of stripped gas is trailing behind the group over a projected scale of 760 kpc. The temperature of the gas along the wake is constant at kT ~ 1.3 keV, which is about a factor of two less than the temperature of the surrounding plasma. We observe a cold front pointing westwards compared to the peak of the group, which indicates that the group is currently not moving in the direction of the main cluster, but is moving along an almost circular orbit. The overall morphology of the group bears remarkable similarities with high-resolution numerical simulations of such structures, which greatly strengthens our understanding of the ram-pressure stripping process

The stripping of a galaxy group diving into the massive cluster A2142

Structure formation in the current Universe operates through the accretion of group-scale systems onto massive clusters. The detection and study of such accreting systems is crucial to understand the build-up of the most massive virialized structures we see today. We report the discovery with XMM-Newton of an irregular X-ray substructure in the outskirts of the massive galaxy cluster Abell 2142. The tip of the X-ray emission coincides with a concentration of galaxies. The bulk of the X-ray emission of this substructure appears to be lagging behind the galaxies and extends over a projected scale of at least 800 kpc. The temperature of the gas in this region is 1.4 keV, which is a factor of ~4 lower than the surrounding medium and is typical of the virialized plasma of a galaxy group with a mass of a few 10^13M_sun. For this reason, we interpret this structure as a galaxy group in the process of being accreted onto the main dark-matter halo. The X-ray structure trailing behind the group is due to gas stripped from its original dark-matter halo as it moves through the intracluster medium (ICM). This is the longest X-ray trail reported to date. For an infall velocity of ~1,200 km s-1 we estimate that the stripped gas has been surviving in the presence of the hot ICM for at least 600 Myr, which exceeds the Spitzer conduction timescale in the medium by a factor of >~400. Such a strong suppression of conductivity is likely related to a tangled magnetic field with small coherence length and to plasma microinstabilities. The long survival time of the low-entropy intragroup medium suggests that the infalling material can eventually settle within the core of the main cluster.Comment: 11 pages, 7 figures, accepted for publication in A&